{"id":11474,"date":"2026-08-26T09:15:47","date_gmt":"2026-08-26T07:15:47","guid":{"rendered":"https:\/\/www.three-tec.ch\/?page_id=11474"},"modified":"2026-08-28T14:25:15","modified_gmt":"2026-08-28T12:25:15","slug":"scale-up","status":"publish","type":"page","link":"https:\/\/www.three-tec.ch\/en\/know-how\/scale-up\/","title":{"rendered":"Scale-up: The Path from the Lab to Production"},"content":{"rendered":"

Scale-up<\/h1>\t\t\t\t\t\n\t\t\tThe Path from the Lab to Production\t\t\n\t

\n\t\t\t\tWhat does \"scale-up\" mean?\n\t\t\t<\/h2>\n\t\t\t\u00a0Scale-up bezeichnet die \u00dcbertragung eines im Labor erfolgreich entwickelten Prozesses auf gr\u00f6ssere Anlagen und schliesslich in die industrielle Produktion – bei gleichbleibender Produktqualit\u00e4t und Reproduzierbarkeit.\u00a0Three-Tec stellt als einer der wenigen Anbieter weltweit Laborger\u00e4te mit Schneckendurchmesser ab 5 mm her. Aufgrund des geringen Materialverbrauchs eigenen sich diese Ger\u00e4te ideal f\u00fcr die Prozessentwicklung und liefern Scale-up-taugliche Resulate. Erfahren Sie mehr \u00fcber unsere Feeding systems<\/a> and Extruders<\/a>.\t\n\t

\n\t\t\t\tWhy is scaling up important?\n\t\t\t<\/h2>\n\t\t\tMany processes initially work only under laboratory conditions. For commercial production, they must be scaled up to higher throughputs in a reproducible manner.\t\n\t

\n\t\t\t\tTest laboratory\n\t\t\t<\/h2>\n\t\t\t

At Three-Tec\u2019s testing and application lab, existing and new processes can be developed and optimized under realistic conditions before being transferred to production. Learn more on our page about the Test laboratory<\/a> or in the article Tests with your original products in our laboratory<\/a>.<\/p>\t\n\t

\n\t\t\t\tFrequently Asked Questions\n\t\t\t<\/h2>\n\t\t\t

What steps are involved in a typical scale-up process?<\/strong>A successful scale-up typically involves six steps: a laboratory feasibility study, formulation development and optimization, definition of critical process parameters, testing on pilot plants, transfer to production facilities, and final process validation.\u00a0Which process parameters are particularly critical during scale-up?<\/strong>The most important factors include residence time, shear rate, temperature profile, material throughput, mixing intensity, and dosing accuracy. Even small deviations in these parameters can affect product quality. Only documented processes can be reliably replicated.\u00a0Why is precise dosing important for a successful scale-up?<\/strong>A stable and consistent supply of raw materials is essential for reliably transferring process results from the laboratory to larger-scale facilities.\u00a0Why do modular systems make scale-up easier?<\/strong>If laboratory equipment and production facilities have similar screw geometries and comparable process conditions, a process developed in the laboratory can be transferred to production much more easily and reliably.\u00a0<\/p>\t\n\t

\n\t\t\t\tOther Topics\n\t\t\t<\/h2>\nDosing Technology: Fundamentals, Methods, and Applications<\/a>Extrusion Explained Simply: From Raw Material to Final Product<\/a>Polymer Compounding: Targeted Optimization of Materials<\/a>Extrusion in the Pharmaceutical, Battery, and Research Industries<\/a>Laboratory Extruders for Research, Development, and Scale-Up<\/a>","protected":false},"excerpt":{"rendered":"

Scale-up Der Weg vom Labor zur Produktion Was bedeutet Scale-up? \u00a0Scale-up bezeichnet die \u00dcbertragung eines im Labor erfolgreich entwickelten Prozesses auf gr\u00f6ssere Anlagen und schliesslich in die industrielle Produktion – bei gleichbleibender Produktqualit\u00e4t und Reproduzierbarkeit.\u00a0Three-Tec stellt als einer der wenigen Anbieter weltweit Laborger\u00e4te mit Schneckendurchmesser ab 5 mm her. Aufgrund des geringen Materialverbrauchs eigenen sich […]<\/p>\n","protected":false},"author":4,"featured_media":0,"parent":1870,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"_seopress_titles_title":"Scale-up: | Three-Tec","_seopress_titles_desc":"Scale-up: Der Weg vom Labor zur 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